RNA Gene Editing might hinder Virus Replication.


RNA editing is a molecular process through which some cells can make discrete changes to specific nucleotide sequences within an RNA molecule, after it has been generated by RNA polymerase.

The gene editing technique CRISPR is looking into treating all manner of genetically linked conditions. All these while, it’s been restricted to just tweaking DNA which is the manipulation of DNA to achieve certain results, not really the RNA responsible for carrying protein sequence up to regulating the expression of genes. It is kinda great to know that this may change in no distant time, as scientists have discovered that a mouth bacterium called Leptotrichia shahii can be programmed in a way to breakdown any desired RNA. This will enable the killing of cancer cells using a mechanism that denies the opportunity of vital proteins to be made and also enable the tearing down of viruses localized around RNA.

Although this could be a potential cure, it isn’t yet, this is because researches are still working on refining the approach used before it can actually be said if it can really work in humans or even work as effective as they think it would.

You know this will really be a huge breakthrough in the world of genetics if it works right? So many of those terrible diseases will eventually be curable, whew!

CRISPR – Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short repetitions of base sequences. Each repetition is followed by short segments of “spacer DNA” from previous exposures to a bacteriophage virus or plasmid.

The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages and provides a form of acquired immunity. CRISPR spacers recognize and cut these exogenous genetic elements in a manner analogous to RNA interference in eukaryotic organisms. CRISPRs are found in approximately 40% of sequenced bacterial genomes and 90% of sequenced archaea.

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